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Celiac Disease, Genetic Testing

Includes 2 tests
Blood, Other
2 Days

Genetic testing for celiac disease is used as an adjunct to screening patients with potential celiac disease.

More information

Celiac disease (gluten intolerance) is an enteropathy with a solid genetic background. The disease is characterized by permanent intolerance to the gluten protein found in wheat, rye, and barley. It affects about 1 in every 100-300 people, though only 1 in 8 know they are concerned as the symptoms can be mild or non-specific. The incidence of celiac disease is more prevalent in certain autoimmune disorders such as insulin-dependent diabetes (6%), thyroiditis (2 to 4%), and Sjogren's syndrome (5%). It is also more prevalent in patients with Down syndrome (5 to 12%), Turner syndrome (3%), Williams syndrome (3 to 10%), and IgA selective deficiency (2 to 10%).

Environmental, immunological, and genetic factors play important roles in the pathogenesis of celiac disease. Celiac disease is closely linked to specific molecules, HLA-DQ2 and HLA-DQ8, encoded by the HLA-DQA1 and HLA-DQB1 genes.

A negative test for variants of the celiac disease-associated HLA-DQA1 and HLA-DQB1 genes categorically excludes the diagnosis of celiac disease. However, molecular screening of genes alone cannot diagnose celiac disease because only a small percentage of individuals with positive testing for these genes will develop it.

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Important Note

Laboratory test results are the most important parameter for diagnosing and monitoring all pathological conditions. Between 70% and 80% of diagnostic decisions are based on laboratory tests. The correct interpretation of laboratory results allows a doctor to distinguish "healthy" from "diseased."

Laboratory test results should not be interpreted from the numerical result of a single analysis. Test results should be analyzed based on each case and family history, clinical findings, and the results of other laboratory tests and information. Your physician should explain the importance of your test results.

At Diagnostiki Athinon, we answer any questions you may have about the test you perform in our laboratory, and we contact your doctor to get the best possible medical care.

Additional information
Tests includedIncludes 2 tests
Sample Blood, Other
Procedure completion test
Step 1

Purchase the test you want online

Select the tests you wish, through the most complete range of Preventive and Functional Medicine tests and purchase them online.

Step 2


We send you the certified package - sampling collection kit, to collect your sample, always in accordance with the instructions contained within the kit.

Step 3

Sending your sample

After you have collected your sample, place it in the prepaid shipping package, contact the courier company and send it to our certified laboratory.

Step 4

Receiving the test results

Download your test results easily and securely anytime you want by logging in to your personal account.

Step 1

Book an appointment and buy the test online

Select from the most complete range test of Prevention, Andrology and Diagnostics, book an appointment in real time and purchase them online.

Step 2


Visit the certified laboratory of Diagnostiki Athinon on the date and time you have chosen, to perform the sampling.

Step 3

Receiving the test results

Download your test results easily and securely anytime you want by logging in to your personal account.

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