The measurement of total antibodies (IgM and IgG class) against the Strongyloides parasite is used to diagnose strongyloidiasis.
Roundworm is caused by the parasite Strongyloides stercoralis, a filamentous worm spread mainly in tropical and subtropical regions. Strongyloides stercoralis, has a complex life cycle that begins with the ripening of the filarous larva in the soil. The larvae penetrate the exposed skin and migrate through the bloodstream to the lungs, from where they then ascend to the bronchial tree and are swallowed. Once found in the small intestine, the pharyngeal larva matures into adult worms that enter the intestinal mucosa. Mature females produce eggs that grow in non-infectious rodent forms in the gastrointestinal tract and are eventually released into the faeces. The time from skin penetration to the appearance of Strongyloides in the faeces is about 3 to 4 weeks.
The most common manifestations of the infection are mild and may include abdominal pain, mild diarrhea, nausea and vomiting. At the site of penetration, the skin can be inflammatory and itchy. Migration of the larvae through the lungs and trachea can cause dry cough, wheezing and mild hemoptysis. Eosinophilia in peripheral blood, although common, does not always exist.
In immunosuppressed patients, rod larvae can mature into infectious filar larvae within the gastrointestinal tract and lead to cycles of self-infection. The larvae then penetrate the gastrointestinal mucosa, migrate to the lungs and can complete their life cycle. This type of infection can maintain the host parasite for many years.
Laboratory test results are the most important parameter for the diagnosis and monitoring of all pathological conditions. 70%-80% of diagnostic decisions are based on laboratory tests. Correct interpretation of laboratory results allows a doctor to distinguish "healthy" from "diseased".
Laboratory test results should not be interpreted from the numerical result of a single analysis. Test results should be interpreted in relation to each individual case and family history, clinical findings and the results of other laboratory tests and information. Your personal physician should explain the importance of your test results.
At Diagnostiki Athinon we answer any questions you may have about the test you perform in our laboratory and we contact your doctor to get the best possible medical care.