The measurement of acid phosphatase in semen is used in the investigation of male infertility and the evaluation of prostate function.
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Acid Phosphatase (ACP) is an enzyme (hydrolase) that catalyzes the hydrolysis of various phosphate esters with optimal pH activity in the acidic region. It can be found in high concentrations in the prostate, bones, blood cells, spleen, and other organs. Several molecular enzyme variants are known (isoenzymes), but the prostate isoenzyme has the highest diagnostic value. Semen plasma is one of the richest sources of acid phosphatase and is an essential measurement for assessing prostate function.
Detecting acid phosphatase in semen is essential for assessing gland function and forensic matters when the presence of semen must be proven.
