Serum urea measurement is used to monitor renal function.
Persuasive Information
Urea is produced in the liver as a result of protein metabolism. Urea is transported in the blood to the kidneys and excreted. Since urea is eliminated through the bloodstream by the kidneys, measuring its concentration in the blood tests kidney function and, more specifically, glomerular function. Blood urea is usually determined along with the creatinine level when assessing kidney function. Both of these parameters should be evaluated before administering any nephrotoxic medication.
Possible Interpretations of Pathological Values
- Increase: Acute glomerulonephritis, acute myocardial infarction, congestive heart failure, diabetes mellitus, diarrhea, gastrointestinal bleeding, high protein diet, mercury poisoning, nephrotic syndrome, obstructive uropathy, kidney disease, severe dehydration, severe infection, shock. Medications: Angiotensin-converting enzyme inhibitors, acetaminophen, acyclovir, allopurinol, amantadine, aminoglycosides, amiodarone, amphotericin B, antidepressants, antibiotics, beta-blockers, diuretics, hydroxyurea, methysergide, NSAIDs, contrast agents, streptokinase
- Decrease: Alcohol abuse, celiac disease, low-protein diet, dialysis, hepatitis, increased antidiuretic hormone, liver failure, pregnancy, malnutrition, nephrosis, fluid overload. Medications: Chloramphenicol, streptomycin
Important Note
Laboratory test results are the most critical parameter for diagnosing and monitoring all pathological conditions. Between 70 to 80% of diagnostic decisions are based on laboratory tests. Correctly interpreting laboratory results allows a doctor to distinguish "healthy" from "diseased."
Laboratory test results should not be interpreted from the numerical result of a single analysis. Test results should be analyzed based on each case and family history, clinical findings, and the results of other laboratory tests and information. Your physician should explain the importance of your test results.
At Diagnostiki Athinon, we answer any questions you may have about the test you perform in our laboratory and contact your doctor to ensure you receive the best possible medical care.
