This test checks urine for the presence of tricyclic antidepressants.
Tricyclic antidepressants are a group of drugs with a similar cyclic chemical structure that is often used to treat depression long-term. They work by inhibiting the reuptake of norepinephrine (noradrenaline) and serotonin in the central nervous system and have anticholinergic properties. They are metabolized in the liver, with varying half-lives, and peak approximately 4-8 hours after oral administration.
Toxicity: Confusion, agitation, hallucinations, seizures, coma, arrhythmia, hyperthermia, flushing, mydriasis, death.
The test detects the substances nortriptyline, nordoxepin, trimipramine, amitriptyline, promazine, desipramine, imipramine, clomipramine, doxepin, maprotiline, promethazine.
Important Note
Laboratory test results are the most critical parameter for diagnosing and monitoring all pathological conditions. Between 70 to 80% of diagnostic decisions are based on laboratory tests. Correctly interpreting laboratory results allows a doctor to distinguish "healthy" from "diseased."
Laboratory test results should not be interpreted from the numerical result of a single analysis. Test results should be analyzed based on each case and family history, clinical findings, and the results of other laboratory tests and information. Your physician should explain the importance of your test results.
At Diagnostiki Athinon, we answer any questions you may have about the test you perform in our laboratory and contact your doctor to ensure you receive the best possible medical care.
