Serum phospholipid measurement is used to diagnose lecithin-cholesterol acyltransferase (LCAT) deficiency.
More information
Phospholipids, or "complex lipids," are the largest and most soluble fraction of blood lipids. Phospholipids (which contain phosphorus, fatty acids, and nitrogen) are required for lipid transport and are a significant component of cell membranes. Serum phospholipid determinations are applicable when disorders of lipid metabolism are suspected. However, they are used less frequently today because cholesterol levels or more specific tests are more appropriate. Phospholipid levels in amniotic fluid reflect the level of surfactant and indicate fetal lung maturity.
Possible Interpretations of Pathological Values
- Increase: Diabetes mellitus, biliary cirrhosis, cholestasis, LCAT (lecithin-cholesterol acyltransferase) deficiency, hypothyroidism, cirrhosis, obstructive jaundice, nephrotic syndrome with breast cancer, chronic pancreatitis. Medications: Estrogens, epinephrine, certain phenothiazines
- Decrease: Primary hypolipoproteinemia, Tangier disease, abetalipoproteinemia, low-fat diet. Medications: Antilipidemic agents such as clofibrate
Important Note
Laboratory test results are the most critical parameter for diagnosing and monitoring all pathological conditions. Between 70 to 80% of diagnostic decisions are based on laboratory tests. Correctly interpreting laboratory results allows a doctor to distinguish "healthy" from "diseased."
Laboratory test results should not be interpreted from the numerical result of a single analysis. Test results should be analyzed based on each case and family history, clinical findings, and the results of other laboratory tests and information. Your physician should explain the importance of your test results.
At Diagnostiki Athinon, we answer any questions you may have about the test you perform in our laboratory and contact your doctor to ensure you receive the best possible medical care.
