Serum osmolality measures the number of osmotically active particles in the serum. This test helps assess fluid and electrolyte balance and determine the body's fluid requirements. It also provides valuable information about the patient's hydration status, urine concentration, and antidiuretic hormone (ADH) secretion. Serum osmolality is particularly useful in investigating hyponatremia, which may be caused by sodium loss in the urine or increased fluid in the bloodstream.
Medications affecting measurement: Mineralocorticoids, diuretics.
Possible Interpretation of Pathological Values
- Increase: Acidosis, advanced liver disease, excessive alcohol intake, azotemia, burns, convulsions, dehydration, diabetes insipidus, diabetes mellitus, ethylene glycol overdose, high-protein diet, hyperaldosteronism, hyperbilirubinemia, hypercalcemia, hyperglycemia, hypernatremia, hypokalemia, ketoacidosis, methanol overdose, shock, trauma, uremia
- Decrease: Addison's disease, congestive heart failure, liver cirrhosis, liver failure with ascites, lung cancer, fluid overload, postoperative, syndrome of inappropriate antidiuretic hormone secretion (SIADH)
Important Note
Laboratory test results are the most critical parameter for diagnosing and monitoring all pathological conditions. Between 70 to 80% of diagnostic decisions are based on laboratory tests. Correctly interpreting laboratory results allows a doctor to distinguish "healthy" from "diseased."
Laboratory test results should not be interpreted from the numerical result of a single analysis. Test results should be analyzed based on each case and family history, clinical findings, and the results of other laboratory tests and information. Your physician should explain the importance of your test results.
At Diagnostiki Athinon, we answer any questions you may have about the test you perform in our laboratory and contact your doctor to ensure you receive the best possible medical care.
