Fecal control for the presence of Norovirus antigen is used for laboratory documentation of the virus as a cause of gastroenteritis.
More information
Noroviruses are a genetically heterogeneous group of viruses that contain a single chain of RNA, are not surrounded by an envelope, and belong to the family of Caliciviridae viruses. For decades, this group of viruses has been termed "SRSV, Small Round Structured Viruses," or Norwalk viruses until very recently, when their classification was investigated using modern molecular biology methods. While four different antigenic types of SRSV were initially identified, they eventually resulted in the identification of 3 different types within the genus of Noroviruses. Type 1 (including Norwalk type) and type 2 are associated with human infections, while type 3 is associated with diseases in bovine and porcine animals.
Noroviruses are a significant cause of acute gastroenteritis with a worldwide distribution and very often cause epidemics. They are highly contagious, and the number of viral particles that need to be inoculated to be able to cause disease is only 10. The virus is transmitted by eating contaminated food and water and contact from person to person. The virus is typically transmitted via the fecal-oral route but can also be transmitted through the vomiting particles containing several particles.
The disease is acute after a 24 - 48 hour incubation period, usually mild in intensity, although it can cause severe problems in the elderly and self-limited. Noroviruses’ ability to cause epidemics indoors (schools, institutions, etc.) can create serious public health problems. Infections in newborns, the elderly, and other vulnerable groups can be fatal if not adequately addressed.
Symptoms of Norovirus infection usually include nausea, vomiting (especially in children), diarrhea, and stomach cramps. Low fever, chills, headache, muscle aches, and tiredness sometimes coexist. The onset of the disease is usually sudden, and the patient may feel very ill. The disease is generally self-limiting, with symptoms lasting 1 to 2 days.
The disease can be confirmed by checking for the presence of the virus in the feces (both types of human-infected virus, Type 1 and Type 2, are screened).
Important Note
Laboratory test results are the most critical parameter for diagnosing and monitoring all pathological conditions. Between 70 to 80% of diagnostic decisions are based on laboratory tests. Correctly interpreting laboratory results allows a doctor to distinguish "healthy" from "diseased."
Laboratory test results should not be interpreted from the numerical result of a single analysis. Test results should be analyzed based on each case and family history, clinical findings, and the results of other laboratory tests and information. Your physician should explain the importance of your test results.
At Diagnostiki Athinon, we answer any questions you may have about the test you perform in our laboratory and contact your doctor to ensure you receive the best possible medical care.
