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Non-Alcoholic Fatty Liver Disease, Genetic Testing

Includes 15 tests
Saliva
4 - 5 Weeks
210€

Non-alcoholic fatty liver disease (NAFLD) is a condition in which excess fat accumulates in the liver of people who consume little or no alcohol. Non-alcoholic fatty liver disease can develop into non-alcoholic steatohepatitis (NASH), which is associated with liver inflammation and damage. Lifestyle changes, including diet and exercise, are critical components of management. The assessment of the Polygenic Risk Score for non-alcoholic fatty liver disease is based on the examination of 48 gene polymorphisms.

Genetic testing for non-alcoholic fatty liver disease is included along with 14 other diseases in the Genetic Screening for Gastrointestinal Diseases, Polygenic Risk Score.

Causes and non-genetic risk factors

Non-alcoholic fatty liver disease (NAFLD) is a medical condition in which excess fat accumulates in the liver. Still, unlike alcohol-related liver disease, this accumulation is not caused by excessive alcohol consumption.

Studies propose the following non-genetic factors as responsible for the disease:

  • Overweight or obesity
  • Certain conditions, such as type 2 diabetes mellitus or metabolic syndrome
  • High concentrations of triglycerides or cholesterol
  • High blood pressure
  • A diet rich in fructose, a sugar commonly used to sweeten beverages and foods. The excess of this sugar is converted into lipids and exerts a toxic effect on the liver, similar to that produced by an excess of alcohol
  • Changes in the composition and function of the intestinal microbiota (a set of bacteria present in the digestive tract)
Symptoms

Non-alcoholic fatty liver disease is a silent disease that stands out for its scarce or absent symptomatology. Generally, it does not cause significant liver damage or complications, although it can cause discomfort due to liver enlargement. However, this disease can progress to non-alcoholic steatohepatitis (NASH), which is characterized by inflammation and liver damage, in addition to the accumulation of fat in the organ. Inflammation and liver damage can lead to fibrosis or scarring in the liver, which can eventually develop into cirrhosis. Clinical signs of cirrhosis include yellowing of the skin and eyes (jaundice), enlarged blood vessels under the skin, enlarged spleen, and red palms.

Prevention

Non-alcoholic fatty liver disease (NAFLD) can be prevented through regular physical activity, a healthy diet, and maintaining an appropriate weight. The diet should prioritize foods such as fruits, vegetables, whole grains, and healthy fats while controlling triglyceride and cholesterol levels and reducing the consumption of fructose-rich beverages or foods.

Additional information
Tests includedIncludes 15 tests
Sample Saliva
Results Time4 - 5 Weeks
Procedure completion test
Step 1

Purchase the test you want online

Select the tests you wish, through the most complete range of Preventive and Functional Medicine tests and purchase them online.

Step 2

Sampling

We send you the certified package - sampling collection kit, to collect your sample, always in accordance with the instructions contained within the kit.

Step 3

Sending your sample

After you have collected your sample, place it in the prepaid shipping package, contact the courier company and send it to our certified laboratory.

Step 4

Receiving the test results

Download your test results easily and securely anytime you want by logging in to your personal account.

Step 1

Book an appointment and buy the test online

Select from the most complete range test of Prevention, Andrology and Diagnostics, book an appointment in real time and purchase them online.

Step 2

Sampling

Visit the certified laboratory of Diagnostiki Athinon on the date and time you have chosen, to perform the sampling.

Step 3

Receiving the test results

Download your test results easily and securely anytime you want by logging in to your personal account.

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