Mi-2 beta Antibodies

Screening for antibodies against the Mi-2 beta antigen is performed in patients with the potential for polymyositis, dermatomyositis, and overlap syndrome.

Antibodies against the Mi-2 protein are associated with classical dermatomyositis and are detected in 30% of patients. Antibodies against Mi-2 can also be detected in a small proportion of patients with polymyositis (<10%). The Mi-2 antigen contains two chains, and patients may have antibodies against the Mi-2 alpha or even against the Mi-2 beta antigen chains. There is no known clinical difference between the antibodies directed against the two different Mi-2 chains.

See also: Mi-2 alpha Antibodies

Measurement of antibodies against the Mi-2β antigen is performed by taking a blood sample which can be done:

• At Diagnostiki Athinon - By taking a blood sample in Diagnostiki Athinon. There is no need for prior fasting. Book your appointment in real time and purchase the test online.