Serum iron is used to assess conditions related to the production and destruction of red blood cells, as well as the metabolism and transport of iron.
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Iron (Fe) is an inorganic ion mainly found in hemoglobin. It acts as a carrier of oxygen from the lungs to tissues and indirectly participates in the return of carbon dioxide to the lungs. Although the primary source of iron in the body is food, only a tiny portion of the iron in the food can and is absorbed. Iron is stored in the liver and the reticuloendothelial system in the form of ferritin and hemosiderin and is released when needed to meet the body's requirements. Although iron levels are assumed to be higher in the morning due to daily fluctuations, studies have shown that limiting morning sampling does not improve the reliability of the test results.
Toxicity can occur with an iron over 20 mg/kg body weight.
Possible Interpretations of Pathological Values
- Increase: Acute hepatitis, aplastic anemia, blood transfusion, hemochromatosis, hemolytic anemia, hepatitis, lead poisoning, nephritis, pernicious anemia, polycythemia, ironblastic anemia, thalassemia, vitamin B6 deficiency. Drugs: Alcohol (wine, ethanol), cefotaxime, chloramphenicol, estrogens, ferrous sulfate, methimazole, methotrexate
- Decrease: Blood loss, burns, cancer, gastrectomy, infection, iron deficiency anemia, kwashiorkor, malabsorption, nephrosis, post-operative conditions, pregnancy, rheumatoid arthritis, schizophrenia (chronic), tetralogy of Fallot, uremia. Medications: Metformin, allopurinol, aspirin, cholestyramine, corticotropin, pergolide, progestogens, risperidone, testosterone
Important Note
Laboratory test results are the most important parameter for diagnosing and monitoring all pathological conditions. Between 70% and 80% of diagnostic decisions are based on laboratory tests. Correct interpretation of laboratory results allows a doctor to distinguish "healthy" from "diseased."
Laboratory test results should not be interpreted solely based on the numerical result of a single analysis. They should be interpreted in relation to each individual case, family history, clinical findings, and the results of other laboratory tests and information. Your physician should explain the importance of your test results.
At Diagnostiki Athinon, we answer any questions you may have about the test you perform in our laboratory and contact your doctor to ensure you receive the best possible medical care.
