In insulin response, 3 specimens, insulin in the blood at specific time intervals in response to oral glucose administration, is measured. It is used to evaluate patients with hypoglycemia and suspected insulin resistance.
Insulin is a hormone produced and stored in the pancreas. It is produced in response to elevated blood glucose after eating and is necessary for transporting and storing glucose, the body's primary energy source. In addition, as insulin helps transport glucose through the bloodstream, it also plays a role in metabolism by regulating glucose levels.
Insulin and glucose levels must maintain a balance. Usually, after a meal, the body metabolizes carbohydrates into glucose. Then the glucose is absorbed into the bloodstream, causing the blood glucose level to rise and stimulating the pancreas to release insulin into the blood. However, as glucose moves into cells, the amount in the blood decreases, and insulin release by the pancreas reduces.
If an individual cannot produce a sufficient amount of insulin, or if the body is not able to process it (insulin resistance), an adequate amount of glucose will not be able to reach all of the cells throughout the body. Unregulated blood glucose can lead to various disorders and complications, including metabolic, kidney, cardiovascular disease, and vision and neurological problems.
Common signs or symptoms of hypoglycemia include:
- Increased heart rate
Additionally, signs or symptoms of insulin resistance may include:
- A large waistline
- High blood pressure
- High triglycerides
- Low HDL cholesterol
- Fasting glucose level > 105 mg/dL
- Patches of dark, velvety skin
Laboratory test results are the most important parameter for the diagnosis and monitoring of all pathological conditions. 70%-80% of diagnostic decisions are based on laboratory tests. The correct interpretation of laboratory results allows a doctor to distinguish "healthy" from "diseased".
Laboratory test results should not be interpreted from the numerical result of a single analysis. Test results should be interpreted in relation to each individual case and family history, clinical findings, and the results of other laboratory tests and information. Your personal physician should explain the importance of your test results.
At Diagnostiki Athinon we answer any questions you may have about the test you perform in our laboratory and we contact your doctor to get the best possible medical care.