A nasal smear for eosinophil count is used to investigate allergic rhinitis.
More information
The appearance of eosinophils in nasal swabs has been reported in allergic conditions, including drug allergies. The nasal smear for eosinophil count is a reliable test with relatively high specificity, especially in children with seasonal allergic rhinitis. The nasal secretions of patients with allergic rhinitis usually contain increased numbers of eosinophils. In allergy, the pathological picture is characterized by eosinophilic infiltration and edema. When eosinophils are found in the secretions, they indicate the presence of an allergic process.
In purely inflammatory or infectious processes affecting the same structures, neutrophils express the cytological response. In allergic conditions, the degree of eosinophilia in the secretions is proportional to the severity of the symptoms and reactions. In milder cases of nasal allergy, eosinophils are present in comparatively small numbers, whereas in hay fever, large numbers of the cells are found. The infiltration of neutrophilic granulocytes characterizes acute, subacute, and chronic infections, and consequently, only this type of cell is found in the secretions.
Allergic rhinitis is an IgE-mediated hypersensitivity reaction in the nasal mucosa characterized by sneezing, itching, watery nasal discharge, and a feeling of nasal obstruction.
Important Note
Laboratory test results are the most critical parameter for diagnosing and monitoring all pathological conditions. Between 70 to 80% of diagnostic decisions are based on laboratory tests. Correctly interpreting laboratory results allows a doctor to distinguish "healthy" from "diseased."
Laboratory test results should not be interpreted from the numerical result of a single analysis. Test results should be analyzed based on each case and family history, clinical findings, and the results of other laboratory tests and information. Your physician should explain the importance of your test results.
At Diagnostiki Athinon, we answer any questions you may have about the test you perform in our laboratory and contact your doctor to ensure you receive the best possible medical care.
