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Dupuytren's Disease, Genetic Testing

Includes 12 tests
Saliva
4 - 5 Weeks
210€

Dupuytren's disease, also known as Dupuytren's contracture, is a condition in which the tissues under the skin of the palm and fingers thicken, causing the fingers to curl inward. This can limit the function of the hand. Treatment options include injections and surgery to release dense tissue. The assessment of the Polygenic Risk Score for Dupuytren's disease is based on the examination of 42 gene polymorphisms.

Genetic testing for Dupuytren's disease is included along with 11 other diseases in the Genetic Screening for Musculoskeletal Diseases, Polygenic Risk Score.

Causes and non-genetic risk factors

The causes that give rise to the disease are unknown. Studies have shown that it has a significant genetic component and that, in addition, there are risk factors that favor its appearance, such as the following:

  • Age: It occurs more frequently after the age of 50
  • Sex: It is more common in men than in women, and the symptoms are usually more evident in men
  • Ethnic origin: It is more common in people from Northern Europe
  • Habitual use of vibratory machinery
  • Some diseases such as diabetes, liver disease or epilepsy
  • Habitual consumption of tobacco and alcohol
Symptoms

The first physical manifestation of the disease is the presence of a nodule in the palm that may be tender but is painless. Over time, a cord may form that extends to the fingers and closes the hand. In the advanced stages of the disease, affected persons cannot fully open their hands and have trouble grasping objects.

Prevention

So far, there are no known measures to prevent Dupuytren`s disease. However, once diagnosed, there are treatments that help manage the pathology, such as surgery (in severe cases), radiation therapy (especially in early stages), or steroid or collagenase injections. Any treatment can provide early relief, as the contraction usually returns with time.

Additional information
Tests includedIncludes 12 tests
Sample Saliva
Results Time4 - 5 Weeks
Procedure completion test
Step 1

Purchase the test you want online

Select the tests you wish, through the most complete range of Preventive and Functional Medicine tests and purchase them online.

Step 2

Sampling

We send you the certified package - sampling collection kit, to collect your sample, always in accordance with the instructions contained within the kit.

Step 3

Sending your sample

After you have collected your sample, place it in the prepaid shipping package, contact the courier company and send it to our certified laboratory.

Step 4

Receiving the test results

Download your test results easily and securely anytime you want by logging in to your personal account.

Step 1

Book an appointment and buy the test online

Select from the most complete range test of Prevention, Andrology and Diagnostics, book an appointment in real time and purchase them online.

Step 2

Sampling

Visit the certified laboratory of Diagnostiki Athinon on the date and time you have chosen, to perform the sampling.

Step 3

Receiving the test results

Download your test results easily and securely anytime you want by logging in to your personal account.

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