DPPX Antibodies

Screening for DPPX autoantibodies is used in suspected autoimmune encephalitis as well as in encephalomyelopathy of unknown etiology and in progressive encephalomyelitis with rigidity and myoclonus (PERM).

Testing for anti-neuronal antibodies against the DPPX protein (Dipeptidyl Aminopeptidase-like Protein 6) in serum or cerebrospinal fluid (CSF) is of particular importance in the differential diagnosis of encephalitis. DPPX protein is mainly produced in brain tissue and interacts with the KV4 potassium channel. The DPPX protein is an important regulator of membrane viability in hippocampal CA1 pyramidal cells. Antibodies against DPPX can lead to autoimmune encephalitis.

DPPX belongs to the group of extracellular antigens.

Measurement for the presence of DPPX antibodies is performed by taking a blood sample which can be done:

• At Diagnostiki Athinon - By taking a blood sample in Diagnostiki Athinon. There is no need for prior fasting. Book your appointment in real-time and purchase the test online