Vitamin B6 measurement is used to control subvitaminosis and to monitor supplement therapy as well as to investigate patients with progressive nerve compression disorders, such as carpal tunnel syndrome.
Vitamin B6 refers to a total of three water-soluble vitamins: pyridoxine, pyridoxal and pyridoxamine. After absorption, pyridoxine is converted to the active forms of pyridoxal and pyridoxamine. These vitamins are found in many foods, including meat, egg yolk, fish, poultry, whole grains (wheat, rye, barley, rice, soybeans) and vegetables. Complex B vitamins are important in the functioning of the central nervous system and in the synthesis of hemoglobin heme and function as coenzymes in amino acid metabolism and glycogenolysis. Because vitamin B6 is partially destroyed by heat, overheating of infants makes infants particularly prone to vitamin B6 deficiency.
Symptoms of vitamin B6 deficiency can include colic, reflex increase, convulsions, and irritability. Vitamin B6 levels tend to decrease with age. Low levels of vitamin B6 have been associated with high levels of homocysteine and an increased risk of vascular disease as well as peripheral neuropathy.
Possible Interpretations of Pathological Values
- Increase: Excessive intake of vitamin B6 supplements
- Decrease: Alcoholism (chronic), anemia (ferroblastic), diabetes (pregnancy), poor dietary intake, lactation, malabsorption, malnutrition, pregnancy, inflammatory bowel disease. Medications: Cycloserine, disulfiram, hydrazine, isoniazid, levodopa, oral contraceptives, penicillamine, pyrazinic acid
Important Note
Laboratory test results are the most important parameter for the diagnosis and monitoring of all pathological conditions. 70%-80% of diagnostic decisions are based on laboratory tests. Correct interpretation of laboratory results allows a doctor to distinguish "healthy" from "diseased".
Laboratory test results should not be interpreted from the numerical result of a single analysis. Test results should be interpreted in relation to each individual case and family history, clinical findings and the results of other laboratory tests and information. Your personal physician should explain the importance of your test results.
At Diagnostiki Athinon we answer any questions you may have about the test you perform in our laboratory and we contact your doctor to get the best possible medical care.
