URL path: Index page // Metanephrines, Urine 24h

Metanephrines, Urine 24h

Includes 1 test
Blood
25€

Urine metanephrine measurement is used for the diagnosis and laboratory documentation of catecholamine-secreting tumors such as pheochromocytes and paragangliomas as well as confirmation of meta-epinephrine plasma measurements.

More information

Metanephrine measurement is used to evaluate adrenal function. Metanephrine is usually determined when a patient with hypertension is suspected of having pheochromocytoma, which is a tumor of the adrenal medulla. Less than 1% of hypertensive patients have pheochromocytosis. Metanephrines (normetetanephrine and metanephrine) are the main substances that are formed in the adrenal medulla, released into the bloodstream and excreted in the urine. These substances contain a catechol nucleus and an amine group and therefore belong to the catecholamines. Metanephrine and normomethanephrine are metabolites of epinephrine and norepinephrine, respectively. Metanephrine and normomethanephrine are then metabolized to vanillylmandelic acid (VMA).

The traditional method of testing is a 24-hour urine test (89-100% sensitivity), because blood testing has many interfering factors. Determination of metanephrines is the best test for the diagnosis of pheochromocytosis because metanephrine levels are not influenced by factors that influence catecholamine levels, such as, changes in posture, exercise, surgical stress. Metanephrine levels are also better correlated to tumor size and have fewer interventions than taking catecholamines.

Possible Interpretations of Pathological Values
 
  • Increase: Adrenal tumors, brain tumors, ganglion neuroblastoma, ganglion neuroma, neuroblastoma, pheochromocytosis hypertension, malignant pheochromocytoma, pheochromocytoma, enlarged metastasis, malignant myasthenia

 

 

Important Note

Laboratory test results are the most important parameter for the diagnosis and monitoring of all pathological conditions. 70%-80% of diagnostic decisions are based on laboratory tests. Correct interpretation of laboratory results allows a doctor to distinguish "healthy" from "diseased".

Laboratory test results should not be interpreted from the numerical result of a single analysis. Test results should be interpreted in relation to each individual case and family history, clinical findings and the results of other laboratory tests and information. Your personal physician should explain the importance of your test results.

At Diagnostiki Athinon we answer any questions you may have about the test you perform in our laboratory and we contact your doctor to get the best possible medical care.

Additional information
Tests includedIncludes 1 test
Sample Blood
Procedure completion test
Step 1

Book an appointment and buy the test online

Select from the most complete range test of Prevention, Andrology and Diagnostics, book an appointment in real time and purchase them online.

Step 2

Sampling

Visit the certified laboratory of Diagnostiki Athinon on the date and time you have chosen, to perform the sampling.

Step 3

Receiving the test results

Download your test results easily and securely anytime you want by logging in to your personal account.

Share it