Serum lipase measurement is used in the investigation of pancreatic diseases and in particular of pancreatitis.
Lipase is a pancreatic enzyme that converts fats and triglycerides into fatty acids and glycerol. The pancreas is the only organ in the body that has significant lipase activity. In acute pancreatitis, serum lipase levels begin to increase 2-6 hours after the onset of the disease, peak at 12-30 hours and remain elevated and then decrease for the next 2-4 days. Lipase increases and decreases along with amylase in acute pancreatitis, but it is a more specific indicator than amylase for this condition.
During pregnancy lipase levels may rise slightly.
Possible Interpretations of Pathological Values
- Increase: Cholecystitis, cirrhosis, duodenal ulcer, fat embolism, fructose malabsorption, abdominal pain, pancreatic carcinoma, pancreatic trauma, pancreatitis, peritonitis, kidney disease, ileus. Medications: Ethanol, heparin, analgesics.
Laboratory test results are the most important parameter for the diagnosis and monitoring of all pathological conditions. 70%-80% of diagnostic decisions are based on laboratory tests. Correct interpretation of laboratory results allows a doctor to distinguish "healthy" from "diseased".
Laboratory test results should not be interpreted from the numerical result of a single analysis. Test results should be interpreted in relation to each individual case and family history, clinical findings and the results of other laboratory tests and information. Your personal physician should explain the importance of your test results.
At Diagnostiki Athinon we answer any questions you may have about the test you perform in our laboratory and we contact your doctor to get the best possible medical care.