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Celiac Disease, Molecular Detection

Includes 1 test
Blood
150€

Molecular screening for celiac disease is used as an adjunct to screening patients with potential celiac disease.

More information

Celiac disease (gluten intolerance) is an enteropathy with a strong genetic background. The disease is characterized by permanent intolerance to the gluten protein found in wheat, rye and barley. It affects about 1 in every 100-300 people, though only 1 in 8 know they are affected as the symptoms can be mild or non-specific. The incidence of celiac disease is more prevalent in certain autoimmune disorders such as insulin-dependent diabetes (6%), thyroiditis (2 to 4%) and Sjogren's syndrome (5%). It is also more prevalent in patients with Down Syndrome (5 to 12%), Turner Syndrome (3%), Williams Syndrome (3 to 10%) and IgA Selective Deficiency (2 to 10%).

Environmental, immunological and genetic factors play an important role in the pathogenesis of celiac disease. Celiac disease is closely linked to specific molecules, HLA-DQ2 and HLA-DQ8, encoded by the HLA-DQA1 and HLA-DQB1 genes.

 

A negative test for variants of the celiac disease-associated HLA-DQA1 and HLA-DQB1 genes categorically excludes the diagnosis of celiac disease. However, molecular screening of genes alone cannot make a diagnosis of celiac disease, because only a small percentage of individuals with a positive screening for these genes will develop celiac disease.

 

 

 

Important Note

Laboratory test results are the most important parameter for the diagnosis and monitoring of all pathological conditions. 70%-80% of diagnostic decisions are based on laboratory tests. Correct interpretation of laboratory results allows a doctor to distinguish "healthy" from "diseased".

Laboratory test results should not be interpreted from the numerical result of a single analysis. Test results should be interpreted in relation to each individual case and family history, clinical findings and the results of other laboratory tests and information. Your personal physician should explain the importance of your test results.

At Diagnostiki Athinon we answer any questions you may have about the test you perform in our laboratory and we contact your doctor to get the best possible medical care.

Additional information
Tests includedIncludes 1 test
Sample Blood
Procedure completion test
Step 1

Book an appointment and buy the test online

Select from the most complete range test of Prevention, Andrology and Diagnostics, book an appointment in real time and purchase them online.

Step 2

Sampling

Visit the certified laboratory of Diagnostiki Athinon on the date and time you have chosen, to perform the sampling.

Step 3

Receiving the test results

Download your test results easily and securely anytime you want by logging in to your personal account.

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